Abstract Background The mitogen-activated protein kinase (MAPK) signaling pathway is frequently hyperactivated in malignant melanoma and its inhibition has proved to be an efficient treatment option for cases harboring BRAFV600 mutations (BRAFMut).However, there is still a significant need for effective targeted therapies for patients with other me
Background: Citrus yellow vein-clearing virus (CYVCV) is a Mandarivirus that causes great economic losses in lemon production.CYVCV read more infection is associated with obvious yellow vein-clearing disease symptoms and is directly regulated by plant hormone responses.Methods: To understand how lemon plants respond to CYVCV infection, we performed
Chondromas usually affect the small bones of hand and feet and account for only 0.5% of all intracranial tumors.We present a case of a giant, supratentorial meningeal chondroma in a 19-year old male patient and discuss the preoperative diagnostic findings as well as the appropriate treatment options.A 19-old male presented with headache, new onset